天德悅(北京)生物科技有限責任公司
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        PCNA Mouse mAb(12D10)
        Proliferating Cell Nuclear Antigen antibody, DNA polymerase delta auxiliary protein antibody, PCNAR antibody
         
        Cat#: TDY044   |   Source: Mouse   |   Type: Monoclonal   |
        Applications: WB, IHC   Reactivity: H, R, M
        MW.(KDa): 29 Isotype: IgG1

        Applications:          WB-Western blot     IHC-Immunochemistry       IF-Immunofluorescence     IP-Immunoprecipitation     ChIP-Chormatin Immunoprecipitation

        Reactivity:    H-Human  R-Rat  M-Mouse  Mk-Monkey  Dg-Dog  Ch-Chicken  Hm-Hamster  Rb-Rabbit  Sh-Sheep  Pg-Pig

         

        PCNA is a marker for cells in early G1 phase and S phase of the cell cycle. It is found in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6 dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for PCNA. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. 

         

        Applications Specifications Alternative Names

        Western Blot

         

        Western blot analysis of Hela (1), Rat brain (2), NIH 3T3 (3), 293T(4) with PCNA mouse mAb(12D10) diluted at 1:5000.


        Immunohistochemistry

         

        IHC staining of Human breast cancer tissue paraffin-embedded with PCNA mouse mAb12D10diluted at 1:200


         

         

         

         
          Size:
        TDY044C-50μL ¥800
        TDY044F-100μL ¥1500

          New Product:
        ImmunoWay組織病理學抗體
         
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